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Merck

MAB1940

Anti-Fibronectin Antibody

CHEMICON®, mouse monoclonal, DH1

別名:

Anti-CIG, Anti-ED-B, Anti-FINC, Anti-FN, Anti-FNZ, Anti-GFND, Anti-GFND2, Anti-LETS, Anti-MSF, Anti-SMDCF

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この商品について

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

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製品名

Anti-Fibronectin Antibody, cellular, clone DH1, clone DH1, Chemicon®, from mouse

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

DH1, monoclonal

species reactivity

rat, guinea pig, human, rabbit

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_002026.2
NM_054034.2
NM_212474.1
NM_212475.1
NM_212476.1
NM_212478.1
NM_212482.1

UniProt accession no.

P02751

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... FN1(2335)
rabbit ... Fn1(100328589)
rat ... Fn1(25661)

Application

Detect Fibronectin using this Anti-Fibronectin Antibody, cellular, clone DH1 validated for use in WB, IH.
Immunoblotting at 1:1,000

Indirect immunohistochemistry at 1:200-1:400

A 1-hour fixation with 3-3.5% paraformaldehyde in 0.1 M phosphate buffer pH 7.4 is suggested. Shows some reactivity on paraffin sections depending on fixation conditions and time (Latvala et al., 1996).

Final working dilutions must be determined by end user.

Biochem/physiol Actions

Specific for the extra domain of cellular fibronectin (EDA sequence) and thus recognizes only the cellular fibronectin.

Immunogen

Epitope: cellular
Purified fibronectin from Human A8387 fibrosarcoma cells.

Physical form

Format: Purified
In PBS with 1% BSA and 0.1% sodium azide.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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保管分類

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Olaf Voets et al.
PloS one, 12(8), e0182974-e0182974 (2017-08-12)
Phenotypic assays using human primary cells are highly valuable tools for target discovery and validation in drug discovery. Expression knockdown (KD) of such targets in these assays allows the investigation of their role in models of disease processes. Therefore, efficient
Jassim M Al-Hassan et al.
Frontiers in pharmacology, 11, 899-899 (2020-07-07)
Preparations from Arabian Gulf catfish (Arius bilineatus, Val) epidermal gel secretion (PCEGS) effectively heal chronic wounds in diabetic patients. However, specific lipid components of PCEGS that are responsible for various aspects of wound healing are unknown. Here, we report for
Impaired elastogenesis in Hurler disease: dermatan sulfate accumulation linked to deficiency in elastin-binding protein and elastic fiber assembly.
Hinek, A; Wilson, SE
The American Journal of Pathology null
Iqra Mushtaq et al.
iScience, 27(6), 110084-110084 (2024-06-17)
The mutated SCN5A gene encoding defective Nav1.5 protein causes arrhythmic ailments and is associated with enhanced cardiac fibrosis. This study investigated whether SCN5A mutation directly affects cardiac fibroblasts and explored how defective SCN5A relates to cardiac fibrosis. SCN5A knockdown (SCN5AKD)
Katja Vehanen et al.
Acta ophthalmologica, 86(1), 91-96 (2007-08-23)
The use of biopolymers in peribulbar injection for controlled drug delivery provides alternative options to eyedrops and intravitreal or surgical methods. Polymerizable biopolymers are especially likely to have a role because of their particular properties. In liquid form, they can
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関連コンテンツ

Human Stem Cell Systems

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

Data Sheet - MAB1940

MAB1940

グローバルトレードアイテム番号

カタログ番号GTIN
MAB194004053252665417

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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