217503
Cardiotoxin
from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®
別名:
Cardiotoxin, Naja pallida
製品名
Cardiotoxin, Naja pallida,
description
Merck USA index - 14, 1835
assay
≥95% (HPLC)
form
lyophilized solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
solubility
water: 1 mg/mL
shipped in
ambient
storage temp.
2-8°C
Quality Level
Application
Cardiotoxin, Naja pallida has been used:
- to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration
- to induce a skeletal muscle injury into the right TA muscle
- to induce muscle regeneration
Disclaimer
Toxicity: Harmful (C)
General description
Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.
Legal Information
Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes
Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Deficiency of skeletal muscle Agrin contributes to the pathogenesis of age-related sarcopenia in mice
Chen J, et al.
Cell Death & Disease, 15(3), 201-201 (2024)
Snake peptides
Harvey, Alan L
Handbook of Biologically Active Peptides (2013)
DOCK3 regulates normal skeletal muscle regeneration and glucose metabolism
Samani A, et al.
bioRxiv : the preprint server for biology (2023)
Valeria Yartseva et al.
Cell reports, 30(5), 1491-1503 (2020-02-06)
How satellite cells and their progenitors balance differentiation and self-renewal to achieve sustainable tissue regeneration is not well understood. A major roadblock to understanding satellite cell fate decisions has been the difficulty of studying this process in vivo. By visualizing expression
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy
Matias-Valiente L, et al.
Biomedicine and Pharmacotherapy, 170, 116056-116056 (2024)
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 217503-1MGCN | 04055977276800 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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