298711
Diethyl Pyrocarbonate
≥97% (titration), ryanodine inhibitor, liquid
別名:
Diethyl Pyrocarbonate, Diethyl Oxydiformate, DEPC
製品名
Diethyl Pyrocarbonate, Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles.
SMILES string
O(CC)C(=O)OC(=O)OCC
InChI
1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3
InChI key
FFYPMLJYZAEMQB-UHFFFAOYSA-N
description
Merck USA index - 14, 7998
assay
≥97% (titration)
form
liquid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
protect from light
color
clear colorless
solubility
chloroform: soluble
ethanol: soluble
shipped in
ambient
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
Product does not compete with ATP.
Reversible: no
Disclaimer
Toxicity: Harmful (C)
General description
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
Other Notes
Shoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
保管分類
10 - Combustible liquids
wgk
WGK 3
flash_point_f
156.2 °F - closed cup
flash_point_c
69 °C - closed cup
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
グローバルトレードアイテム番号
| カタログ番号 | GTIN |
|---|---|
| 298711-100GMCN | 04055977197952 |
| 298711-25GMCN | 07790788049041 |
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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