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Merck

1.42020

Cyclodextrin HPB

EMPROVE® EXPERT, Ph. Eur., NF

別名:

Cyclodextrin HPB, (2-Hydroxypropyl)-β-Cyclodextrin, HP-B-CD, Hydroxypropyl Betadex

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この商品について

化学式:
C42H70-nO35 · (C3H7O)n
CAS番号:
UNSPSC Code:
12352201
MDL number:
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製品名

Cyclodextrin HPB, EMPROVE® EXPERT, Ph. Eur., NF

agency

NF
Ph. Eur.

product line

EMPROVE® EXPERT

form

solid

mol wt

avg mol wt 1387.2 g/mol

pH

5.0-7.0 (20 g/L in H2O)

solubility

450 g/L

application(s)

liquid formulation
ophthalmics
pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

Quality Level

Application

Cyclodextrin HPB (hydroxypylated β-cyclodextrin) can be used to strongly increase solubility of active pharmaceutical ingredients (APIs) by forming API:cyclodextrin inclusion complexes. It can also increase API stability and safety as well as mask undesired odors and tastes. The broad application range of Cyclodextrin HPB comprises liquid, semi-solid and solid formulations, as well as diverse routes of administration. Due to its low microbial and endotoxin limits, Cyclodextrin HPB Emprove® Expert is especially suitable for high-risk applications.

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

保管分類

11 - Combustible Solids

wgk

WGK 1

flash_point_f

752.0 °F

flash_point_c

> 400 °C


試験成績書(COA)

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以前この製品を購入いただいたことがある場合

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資料

This overview describes the challenges when developing parenteral formulations and strategies to overcome them and reduce the risk of production.

Discover strategies to enhance solubility in injectable formulations using excipients, including cyclodextrins, meglumine, and polyethylene glycols.

This article outlines critical factors in long-term stability of proteins, and how different stabilizers protect again mechanical and thermal stress.

関連コンテンツ

グローバルトレードアイテム番号

カタログ番号GTIN
1.42020.005004027269677787
1.42020.250004027269699956

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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