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Merck

1.03795

Cellvento® 4CHO COMP

chemically defined cell culture medium, ≤1.0 IU/mL endotoxin, pH 5.1-5.6(without supplement), pH 6.7-7.3(with supplement)

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UNSPSC Code:
41106213

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製品名

Cellvento® 4CHO COMP, chemically defined cell culture medium, ≤1.0 IU/mL endotoxin, pH 5.1-5.6(without supplement), pH 6.7-7.3(with supplement)

Quality Level

500

description

shipped with cooling packs

product line

Cellvento®

form

dry powder

technique(s)

cell culture | mammalian: suitable (suspension)

storage temp.

2-8°C

関連するカテゴリー

Application

Cellvento® 4CHO medium should be used as amplification medium and production medium in fed-batch applications. It is recommended to combine it with the companion feed supplement Cellvento® 4Feed in fed-batch manufacturing processes. The medium does not contain hypoxanthine and thymidine to allow a broad utilization, also in dhfr- transfected cells. The feed does not contain glucose to allow a fine tuning of the glucose concentration during fed-batch processes, thus allowing to minimize lactate production. The feed contains sources of both cysteine and tyrosine and should not be supplemented with any additional alkaline feed. This product is intended for research or further manufacturing but not for human or therapeutic use

General description

Cellvento® 4CHO chemically defined cell culture medium has been specially developed for the growth of Chinese Hamster Ovary (CHO) cells and the expression of monoclonal antibodies and recombinant proteins in suspension culture. The formulation is of non-animal origin, chemically defined and contains no hydrolysates or components of unknown composition. Cellvento® 4CHO medium has been formulated without L-glutamine.

Preparation Note

Formulated to contain 23.7 grams of powder per liter of medium.

Legal Information

CELLVENTO is a registered trademark of Merck KGaA, Darmstadt, Germany

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GHS07

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Hazard Classifications

Eye Irrit. 2 - Skin Sens. 1

保管分類

11 - Combustible Solids

wgk

WGK 2

試験成績書（COA）

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資料

Improving Fed-batch Yields in Upstream Bioprocessing

Our step-by-step guide to optimizing media and feed combinations for upstream bioprocessing.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

Advancing Cell Culture: Low-Impurity Iron Sources in Cellvento® 4CHO Medium

Explore how low-impurity iron sources enhance consistency and control in recombinant protein production using Cellvento® 4CHO medium.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

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Amplify Your Upstream Ecosystem

Eliminate the need to clean, autoclave and assemble your traditional glass bioreactors and save days of downtime with the Mobius® 3L Single-use Bioreactor.

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

Successfully Navigate the Regulatory Landscape for Chemicals and Single-Use Consumables

This page summarizes key considerations related to regulatory expectations for biomanufacturing including chemicals and polymeric materials. For chemicals, topics include nitrosamines and elemental impurities, and for polymeric materials such as filters and single-use assemblies, the focus is qualification and extractable and leachable testing.

グローバルトレードアイテム番号

カタログ番号GTIN
1.03795.010004054839113956
1.03795.001004054839113932
1.03795.000104061841197621
1.03795.000304065272075374

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