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GF113 Transforming Growth Factor-β2 Protein, Recombinant human

Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Culture UniProt Number: P61812 Entrez Gene Number: NM_003238.1
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GF113
10 µg  
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      Overview

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      Key Spec Table

      Key ApplicationsSpeciesSourcePurity
      CULTHuman Baculovirus infected High-5 cellsGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
      Description
      Catalogue NumberGF113
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionTransforming Growth Factor-β2 Protein, Recombinant human
      OverviewTransforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.
      Alternate Names
      • TGF-beta2
      References
      Product Information
      HS Code3504 00 19
      PresentationLyophilized from Sodium Citrate, pH 3.5.
      Quality LevelMQ100
      Applications
      ApplicationTransforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.
      Key Applications
      • Cell Culture
      Biological Information
      PurityGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of TGF-Beta2.
      SourceBaculovirus infected High-5 cells
      Specific ActivityDetermined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED(50) was found to be <=0.2ng/ml, corresponding to a specific activity of >=5 x 10e6 units/mg.
      Entrez Gene Number
      Gene Symbol
      • TGFB2
      • Polyergin
      • G-TSF
      • TGF-beta-2
      • MGC116892
      • TGF-beta2
      • Cetermin
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P61812 # TGF-beta 2 has suppressive effects on interleukin-2 dependent T-cell growth.
      SIZE: 414 amino acids; 47748 Da
      SUBUNIT: Homodimer; disulfide-linked.
      SUBCELLULAR LOCATION: Secreted.
      DISEASE: SwissProt: P61812 # A chromosomal aberration involving TGFB2 is found in a family with Peters anomaly [MIM:604229]. Translocation t(1;7)(q41;p21) with HDAC9. Peters anomaly consists of a central corneal leukoma, absence of the posterior corneal stroma and Descemet membrane, and a variable degree of iris and lenticular attachments to the central aspect of the posterior cornea.
      SIMILARITY: SwissProt: P61812 ## Belongs to the TGF-beta family.
      Stem Cell Type
      • Mesenchymal Stem Cells
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsThe lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      GF113 04053252733925

      Documentation

      Transforming Growth Factor-β2 Protein, Recombinant human SDS

      Title

      Safety Data Sheet (SDS) 

      Transforming Growth Factor-β2 Protein, Recombinant human Certificates of Analysis

      TitleLot Number
      R RE EC CO OM MB BI IN NA AN NT T H HU UM MA AN N T TR RA AN NS SF FO OR RM MI IN NG G G GR RO OW WT TH H F FA AC CT TO OR R-β β2 2 3069346
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR -#946;2 - 2151828 2151828
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR - β2 - 3746869 3746869
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR - β2 - 4163720 4163720
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-2 - 2326311 2326311
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β 2 - 2430363 2430363
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2474855
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 3131192
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2726168
      RECOMBINANT HUMAN TRANSFORMING GROWTH FACTOR-β2 2976534
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      Data Sheet

      Title
      Reprogramming Cell Fate and Function Novel Strategies for iPSC Generation, Characterization, and Differentiation

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      Categories

      Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
      Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors