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ABC480 Anti-Dido3 Antibody

Anti-Dido3 Antibody is an antibody against Dido3 for use in Western Blotting and Immunocytochemistry.

Anti-Dido3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: DIDO1, C20orf158, DATF1, KIAA0333 UniProt Number: Q9BTC0
ABC480
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, ICCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC480
      DescriptionAnti-Dido3 Antibody
      Alternate Names
      • Dido3
      • Death-inducer obliterator 1
      • DIO-1
      • hDido1
      • Death-associated transcription factor 1
      • DATF-1
      Background InformationDeath inducer obliterator 3 (Dido3) is a transcription factor encoded by the DIDO1 (also known as BYE1, DIO1, DATF1, DIDO2, DIDO3) gene in human. Three other isoforms, including Dido1 & 2 (isoform 2 & 1, respectively), are also encoded by the same gene through alternative splicing. In addition to early research activities regarding apoptosis-inducing activity of Dido proteins, later studies reveal important roles of Dido1 & Dido3 (isoform 4) in maintaining stem cell genomic stability and self-renewal (PMID 23831028 & 24347171). Dido3 binds histone H3K4me3 in the nucleus. Histone H3T3 or H3T6 phosphorylation causes H3K4 demethylation and Dido3 translocation from chromatin to the mitotic spindle. Anti-Dido3, Cat. No. ABC480, does not cross-react with Dido1 or Dido2.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Dido3 Antibody is an antibody against Dido3 for use in Western Blotting and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: 0.5 µg/mL from a representative lot detected Dido3 in HT-29 cells.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to human Dido3 near the C-Terminus.
      EpitopeNear C-Terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • DIDO1
      • C20orf158
      • DATF1
      • KIAA0333
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~260 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in HT-29 cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Dido3 in 10 µg of HT-29 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC480 04055977158939

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies