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MABS485 Anti-Ido1, clone 8G11 Antibody

Anti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry.

Anti-Ido1, clone 8G11 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: IDO1, IDO, INDO
UniProt Number: P14902
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MABS485
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MWB, FCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS485
      DescriptionAnti-Ido1, clone 8G11 Antibody
      Alternate Names
      • Ido1
      • Indoleamine 2,3-dioxygenase 1
      • IDO-1
      • Indoleamine-pyrrole 2,3-dioxygenase
      Background InformationIndoleamine 2,3-dioxygenase (IDO) is an enzyme that is responsible for converting tryptophan to kynurenines. IDO is expressed by a wide variety of tissues and can be upregulated by interferon gamma. IDO modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response. IDO may be involved in the suppression of the immune response to tumours and blocking the IDO pathway may be a potential target for immunotherapy.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Ido1, clone 8G11 Antibody is an antibody against Ido1 for use in Western Blotting, Flow Cytometry.
      Key Applications
      • Western Blotting
      • Flow Cytometry
      Application NotesWestern Blotting Analysis: A representative lot detected Ido1 in splenic dendric cells from WT or KO mouse tissue lysate (Oberdan Leo, Universite Libre de Bruxelles).
      Flow Cytometry Analysis: A representative lot detected Ido1 in splenic dendric cells from mouse (Oberdan Leo, Universite Libre de Bruxelles).
      Biological Information
      ImmunogenRecombinant protein corresponding to mouse Ido1.
      Clone8G11
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      SpecificityThis antibody does not cross react with Ido2.
      IsotypeIgG2aκ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • IDO1
      • IDO
      • INDO
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~44 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in Ido1-Flag tag transfected HEK293T cell lysate.

      Western Blotting Analysis: 0.5 µg/mL of this antibody detected Ido1 in 10 µg of Ido1-Flag tag transfected HEK293T cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS485 04055977136869

      Documentation

      Anti-Ido1, clone 8G11 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Ido1, clone 8G11 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Ido1, clone 8G11 - 3193866 3193866
      Anti-Ido1, clone 8G11 - 3389912 3389912
      Anti-Ido1, clone 8G11 - 3728241 3728241
      Anti-Ido1, clone 8G11 - 3839054 3839054
      Anti-Ido1, clone 8G11 - 4034285 4034285
      Anti-Ido1, clone 8G11 - 4201251 4201251
      Anti-Ido1, clone 8G11 -2817484 2817484
      Anti-Ido1, clone 8G11 -Q2556989 Q2556989
      Anti-Ido1, clone 8G11 Monoclonal Antibody 2930086

      Technical Info

      Title
      White Paper: Further considerations of antibody validation and usage.

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies