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ABE531 Anti-PRDM1 Antibody

Anti-PRDM1 Antibody is an antibody against PRDM1 for use in Western Blotting.

Anti-PRDM1 Antibody : Ficha de datos de seguridad (MSDS o SDS), certificado de análisis y de calidad (CoA y CoQ), expedientes, folletos y otros documentos disponibles.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Nuclear Receptors Gene Symbol: PRDM1, BLIMP1 UniProt Number: O75626
ABE531
100 µL  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABE531
      DescriptionAnti-PRDM1 Antibody
      Alternate Names
      • PRDM1
      • PR domain zinc finger protein 1
      • BLIMP-1
      • Beta-interferon gene positive regulatory domain I-binding factor
      • PR domain-containing protein 1
      • Positive regulatory domain I-binding factor 1
      • PRDI-BF1
      • PRDI-binding factor 1
      Background InformationPR domain zinc finger protein 1 (also known as Beta-interferon gene positive regulatory domain I-binding factor, BLIMP-1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PR domain-containing protein 1) is a transcriptional repressor encoded by the PRDM1 gene (or BLIMP1; Entrez Gene ID 639) in human. PRDM1/PLIMP1 protein silences target genes expression collaboratively with several chromatin-modifying enzymes as co-repressors, including histone deacetylases HDAC1/2, lysine methyltransferase G9a, protein arginine methyltransferase PRMT5, lysine-specific demethylase LSD1, as well as Groucho/Transducin-Like Enhancer of split (Gro/TLE) family of co-repressors. Prdm1/Blimp-1 contains an N-terminal PR/SET domain, a central proline- and serine-rich region, and 5 carboxy-terminal zinc fingers. Cat. No. ABE531, Anti-PRDM1.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-PRDM1 Antibody is an antibody against PRDM1 for use in Western Blotting.
      Key Applications
      • Western Blotting
      Application NotesWestern Blotting Analysis: A 1:125 dilution from a representative lot detected PRDM1 in 10 µg of HL-60 cell lysate.
      Biological Information
      ImmunogenHis-tagged recombinant protein corresponding to human PRDM1.
      EpitopeUnknown
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • PRDM1
      • BLIMP1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~105 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in SR cell lysate.

      Western Blotting Analysis: A 1:1,000 dilution of this antibody detected PRDM1 in 10 µg of SR cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      ABE531 04055977163964

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      Categorías

      Life Science Research > Antibodies and Assays > Primary Antibodies