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MABC563 Anti-Kallikrein 2/KLK2 Antibody, clone 4F2.3

Anti-Kallikrein 2/KLK2 Antibody, clone 4F2.3 is an antibody against Kallikrein 2/KLK2 for use in Western Blotting and Immunohistochemistry.

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Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KLK2 UniProt Number: P20151
MABC563
100 µg  
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      Tabla espec. clave

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC563
      DescriptionAnti-Kallikrein 2/KLK2 Antibody, clone 4F2.3
      Alternate Names
      • Kallikrein 2
      • KLK2
      • Glandular kallikrein-1
      • hGK-1
      • Tissue kallikrein-2
      Background InformationKallikrein-2, also known as Glandular kallikrein-1 (hGK-1) or Tissue kallikrein-2, is encoded by the KLK2 gene. Kallikrein-2 is a serine protease produced by secretory epithelial cells in the prostate. Kallikrein-2 cleaves Met-Lys and Arg-Ser amide linkages in kininogen to release Lys-bradykinin. It is also known to activate the proforms of prostate-specific antigen (PSA) and urokinase type plasminogen activator (uPA), as well as inactivate plasminogen activator inhibitor-1 (PAI-1). both PSA and Kallikrein-2 are used as prostate cancer markers.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Kallikrein 2/KLK2 Antibody, clone 4F2.3 is an antibody against Kallikrein 2/KLK2 for use in Western Blotting and Immunohistochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Kallikrein 2/KLK2 in human prostate tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to human Kallikrein 2/KLK2.
      Clone4F2.3
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG1κ
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • KLK2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~30 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in LNCaP cell lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Kallikrein 2/KLK2 in 10 µg of LNCaP cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Número de referencia GTIN
      MABC563 04055977159295