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505724 Rotigotine Hydrochloride - CAS 125572-93-2 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (6S)-5,6,7,8-Tetrahydro-6-[propyl[2­-(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride, Dopamine Receptor Agonist, Rotigotine Hydrochloride, Neupro

Primary Target: D3
505724
  
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      Overview

      Key Spec Table

      CAS #Empirical Formula
      125572-93-2C₁₉H₂₅NOS•HCl
      Description
      Overview

      This product has been discontinued.



      A highly potent non-ergoline dopamine D2 and D3 receptor agonist (Ki = 13 and 0.71 nM for D2 and D3 respectively). Also displays significant affinity for 5-HT1A and adrenergic α2B receptors. Transdermally used in treatment of Parkinson′s disease and restless legs syndrome.
      Catalogue Number505724
      Brand Family Calbiochem®
      Synonyms(6S)-5,6,7,8-Tetrahydro-6-[propyl[2­-(2-thienyl)ethyl]amino]-1-naphthalenol Hydrochloride, Dopamine Receptor Agonist, Rotigotine Hydrochloride, Neupro
      References
      ReferencesSplinter, M. Y. 2007. Ann. Pharmacother. 41, 285.
      Pfeiffer, R. F. 2002. Drugs Aging. 19, 561.
      Product Information
      CAS number125572-93-2
      FormWhite solid
      Hill FormulaC₁₉H₂₅NOS•HCl
      Chemical formulaC₁₉H₂₅NOS•HCl
      Structure formula ImageStructure formula Image
      Biological Information
      Primary TargetD3
      Primary Target K<sub>i</sub>0.71 nM for D3
      Purity≥99% by HPLC
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      505724 0