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MABF1503 Anti-IL-4 (mouse), APC, clone 11B11 Antibody

This rat monoclonal Anti-IL-4 Antibody (mouse), APC, clone 11B11, Cat. No. MABF1503 is validated for use in Flow Cytometry, for the detection of IL-4.

Anti-IL-4 (mouse), APC, clone 11B11 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology Gene Symbol: Il4, Il-4 UniProt Number: P07750
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MABF1503
25 μg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      MFCRAPCMonoclonal Antibody
      Description
      Catalogue NumberMABF1503
      DescriptionAnti-IL-4 (mouse), APC, clone 11B11 Antibody
      Alternate Names
      • Interleukin-4 (IL-4)
      • B-cell IgG differentiation factor
      • B-cell growth factor 1
      • B-cell stimulatory factor 1 (BSF-1)
      • IGG1 induction factor
      • Lymphocyte stimulatory factor 1
      • IL-4
      Background InformationThe 11B11 antibody binds to mouse Interleukin-4 (IL-4), a 14 kDa cytokine that is largely secreted by activated T cells of the Th2 subset, and to some degree by NKT and mast cells. This cytokine acts as a stimulatory factor for B cells, inducing their proliferation and differentiation, as well as playing a role in immunoglobulin class-switching. IL-4 may also provide autocrine stimulation for T cells, and affect the function of antigen presenting cells such as macrophages and dendritic cells. IL-4 can bind and signal via three cell surface receptor types: CD124 by itself, CD124 in combination with the common gamma chain (type I complex), or CD124 combined with CD213a1 (type II complex).The 11B11 antibody is widely used for detection of intracellular levels of IL-4 protein by flow cytometry, as well as for analysis of soluble cytokine as measured by ELISA, and in functional assays to neutralization cytokine-receptor interactions.
      References
      Product Information
      FormatAPC
      PresentationPurified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.
      Quality LevelMQ100
      Applications
      ApplicationThis rat monoclonal Anti-IL-4 Antibody (mouse), APC, clone 11B11, Cat. No. MABF1503 is validated for use in Flow Cytometry, for the detection of IL-4.
      Key Applications
      • Flow Cytometry
      Biological Information
      ImmunogenImmunogen information for this antibody is proprietary information.
      Clone11B11
      ConcentrationPlease refer to lot specific datasheet.
      HostRat
      IsotypeIgG1κ
      Species Reactivity
      • Mouse
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • Il4
      • Il-4
      Purification MethodPurified by size-exclusion chromatography
      UniProt Number
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceThis monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

      Flow Cytometry Analysis: 0.5 μg from a representative lot detected IL-4 in one million C57Bl/6 splenocytes.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
      Packaging Information
      Material Size25 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABF1503 04055977293340

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies