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ABT259 Anti-Fibrinogen gamma chain Antibody

Anti-Fibrinogen gamma chain Antibody is an antibody against Fibrinogen gamma chain for use in Immunohistochemistry and Immunocytochemistry.

Anti-Fibrinogen gamma chain Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Adhesion (CAMs) Gene Symbol: Fgg UniProt Number: Q8VCM7
ABT259
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABT259
      DescriptionAnti-Fibrinogen gamma chain Antibody
      Alternate Names
      • Fibrinogen gamma chain
      Background InformationThe gamma component of fibrinogen is a glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. Various cleavage fragments of fibrinogen and fibrin also regulate cell adhesion, vasoconstricting, chemotaxis, and mitosis. Disorders caused by gamma chain mutations include dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants, the common gammaA and the less abundant gamma'.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationAnti-Fibrinogen gamma chain Antibody is an antibody against Fibrinogen gamma chain for use in Immunohistochemistry and Immunocytochemistry.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Fibrinogen gamma chain in mouse kidney and mouse liver tissue.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the fibrinogen C-terminal domain of mouse Fibrinogen gamma chain.
      EpitopeFibrinogen C-terminal Domain
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Mouse
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Fgg
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~55 kDa observed. The calculated molecular weight is 49 kDa, however Fibrinogen gamma chain has been shown as a ~55 kDa band due to glycosylation (Nickerson, J.M., et al. (1981). Biochemistry. 20:2818-2821).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse liver tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Fibrinogen gamma chain in 10 µg of mouse liver tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABT259 04055977136326

      Documentation

      Anti-Fibrinogen gamma chain Antibody Certificates of Analysis

      TitleLot Number
      Anti-Fibrinogen gamma chain - 3249413 3249413
      Anti-Fibrinogen gamma chain - 3397943 3397943
      Anti-Fibrinogen gamma chain -Q2556980 Q2556980

      References

      Reference overviewPub Med ID
      Biochemistry
      Nickerson, JM; Fuller, GM
      Biochemistry  20  2818-21  1981

      Show Abstract       		7248249 7248249

      Technical Info

      Title
      White Paper: Further considerations of antibody validation and usage.