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05-23-0050 Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem

An immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CRF

Primary Target: An immunomodulatory neuropeptide
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05-23-0050
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
86784-80-7C₂₀₈H₃₄₄N₆₀O₆₃S₂

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      Description
      OverviewAn immunomodulatory neuropeptide that acts to release ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
      Catalogue Number05-23-0050
      Brand Family Calbiochem®
      SynonymsCRF
      References
      ReferencesBarmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
      Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
      Smith, E.M., et al. 1986. Nature 321, 881.
      Udelsman, R., et al. 1986. Nature 319, 147.
      Product Information
      CAS number86784-80-7
      ATP CompetitiveN
      FormWhite to off-white lyophilized solid
      FormulationSupplied as an acetate salt.
      Hill FormulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
      Chemical formulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
      Hygroscopic Hygroscopic
      ReversibleN
      Sold on the basis of peptide contentY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetAn immunomodulatory neuropeptide
      Purity≥97% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide ContentY
      Peptide SequenceH-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSGM7925000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      05-23-0050-1MG 04055977206890

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Corticotropin Releasing Factor, Human and Rat - CAS 86784-80-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      05-23-0050

      References

      Reference overview
      Barmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
      Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
      Smith, E.M., et al. 1986. Nature 321, 881.
      Udelsman, R., et al. 1986. Nature 319, 147.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision02-April-2009 JSW
      SynonymsCRF
      DescriptionReleases ACTH from the anterior pituitary and stimulates the sympathetic nervous system and adrenal medulla. Functions by reducing hyperpolarizations. Acts as a functional antagonist of inflammatory mediators.
      FormWhite to off-white lyophilized solid
      FormulationSupplied as an acetate salt.
      CAS number86784-80-7
      RTECSGM7925000
      Chemical formulaC₂₀₈H₃₄₄N₆₀O₆₃S₂
      Peptide SequenceH-Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH₂
      Purity≥97% by HPLC
      Solubility5% NH₄OH (prepared with H₂O) (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBarmack, N.H., and Errico, P. 1993. J. Neurosci. 13, 4647.
      Wei, E.T., et al. 1993. Ciba Found. Symp. 172, 258.
      Smith, E.M., et al. 1986. Nature 321, 881.
      Udelsman, R., et al. 1986. Nature 319, 147.