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178221 α₂-Antiplasmin, Human Plasma - Calbiochem

A 452-amino acid glycoprotein present in plasma at about 70 µg/ml.

α₂-Antiplasmin, Human Plasma - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: α₂-Protease Inhibitor, Primary Plasmin Inhibitor

Primary Target: Plasminogen activator-induced lysis of fibrin clots
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178221
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178221-100UG
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      Description
      OverviewA 452-amino acid glycoprotein present in plasma at about 70 µg/ml. Efficiently inhibits the plasminogen activator-induced lysis of fibrin clots. Forms a covalent complex with plasmin and inactivates it.
      Catalogue Number178221
      Brand Family Calbiochem®
      Synonymsα₂-Protease Inhibitor, Primary Plasmin Inhibitor
      References
      ReferencesSchaefer, B.M., et al. 1996. Arch. Dermatol. Res. 288, 122.
      Aoki, N., et al. 1980. Blood 55, 483.
      Saito, H., et al. 1974. Circ. Res. 34, 641.
      Product Information
      Unit of DefinitionOne Inhibitory Unit (I.U.) is defined as the amount of enzyme that will inhibit 1 unit plasmin activity using tosyl-Gly-Pro-Lys-<i>p</i>NA as substrate at 25°C, pH 7.8
      ATP CompetitiveN
      FormSolid
      FormulationLyophilized from 200 mM NaCl, 20 mM Bis-Tris, pH 6.4.
      ReversibleN
      Quality LevelMQ100
      Biological Information
      Primary TargetPlasminogen activator-induced lysis of fibrin clots
      Purity≥95% by SDS-PAGE
      SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
      Specific Activity≥5 I.U./mg protein
      Physicochemical Information
      Cell permeableN
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Global Trade Item Number
      Catalogue Number GTIN
      178221-100UG 04055977223101