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475927 [Nle¹³]-Motilin

475927
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical Formula
      C₁₂₁H₁₉₀N₃₄O₃₅
      Description
      Overview

      This product has been discontinued.





      A stable analog of porcine motilin with full biological activity.
      Catalogue Number475927
      Brand Family Calbiochem®
      SynonymsFVPIFTYGELQRNleQEKERNKGQ
      References
      ReferencesKonturek, S.J., et al. 1977. J. Physiol. 264, 665.
      Strunz, U., et al. 1976. Scand. J. Gastroentrerol. 11, 199.
      Wunsch, E., et al. 1976. Hoppe Seylers Z. Physiol. Chem. 357, 467.
      Ruppin, H., et al. 1975. Scand. J. Gastroentrerol. 10, 199.
      Brown, J.C., et al. 1973. Can. J. Biochem. 51, 533.
      Brown, J.C., et al. 1971. Can J. Physiol. Pharmacol. 49, 399.
      Product Information
      FormWhite to off-white solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₂₁H₁₉₀N₃₄O₃₅
      Chemical formulaC₁₂₁H₁₉₀N₃₄O₃₅
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceH-Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Nle-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      475927 0

      Documentation

      [Nle¹³]-Motilin Certificates of Analysis

      TitleLot Number
      475927

      References

      Reference overview
      Konturek, S.J., et al. 1977. J. Physiol. 264, 665.
      Strunz, U., et al. 1976. Scand. J. Gastroentrerol. 11, 199.
      Wunsch, E., et al. 1976. Hoppe Seylers Z. Physiol. Chem. 357, 467.
      Ruppin, H., et al. 1975. Scand. J. Gastroentrerol. 10, 199.
      Brown, J.C., et al. 1973. Can. J. Biochem. 51, 533.
      Brown, J.C., et al. 1971. Can J. Physiol. Pharmacol. 49, 399.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision11-August-2008 RFH
      SynonymsFVPIFTYGELQRNleQEKERNKGQ
      DescriptionA stable analog of porcine motilin with full biological activity. Increases gastric acid and pepsin output in a dose-dependent manner. Reported to induce contractile responses in duodenal and fundic muscles.
      FormWhite to off-white solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₁₂₁H₁₉₀N₃₄O₃₅
      Peptide SequenceH-Phe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Nle-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln-OH
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesKonturek, S.J., et al. 1977. J. Physiol. 264, 665.
      Strunz, U., et al. 1976. Scand. J. Gastroentrerol. 11, 199.
      Wunsch, E., et al. 1976. Hoppe Seylers Z. Physiol. Chem. 357, 467.
      Ruppin, H., et al. 1975. Scand. J. Gastroentrerol. 10, 199.
      Brown, J.C., et al. 1973. Can. J. Biochem. 51, 533.
      Brown, J.C., et al. 1971. Can J. Physiol. Pharmacol. 49, 399.