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559395 SB 203580, Hydrochloride - CAS 869185-85-3 - Calbiochem

Overview

Key Spec Table

CAS #Empirical Formula
869185-85-3C₂₁H₁₆FN₃OS · HCl

Pricing & Availability

Catalogue Number AvailabilityPackaging Qty/Pack Price Quantity
559395-10MG
Limited Availability
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      559395-1MG
      Limited Availability
Limited Availability
      In Stock 
      Discontinued
      Limited Quantities Available
      Availability to be confirmed
        Remaining : Will advise
          Remaining : Will advise
          Will advise
          Contact Customer Service
          Contact Customer Service

          Plastic ampoule 1 mg
          Price could not be retrieved
          Minimum Quantity is a multiple of
          Maximum Quantity is
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          Description
          OverviewA water-soluble form of the potent MAP kinase inhibitor SB 203580 (Cat. No. 559389).
          Catalogue Number559395
          Brand Family Calbiochem®
          Synonyms4-(4-Fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)1H-imidazole, HCl, p38 MAP Kinase Inhibitor XVI, Hydrochloride
          Product Information
          CAS number869185-85-3
          ATP CompetitiveN
          FormBright yellow solid
          Hill FormulaC₂₁H₁₆FN₃OS · HCl
          Chemical formulaC₂₁H₁₆FN₃OS · HCl
          Hygroscopic Hygroscopic
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Biological Information
          Primary Targetp38 MAP kinase
          Primary Target IC<sub>50</sub>34 nM against p38 MAP kinase in vitro, 600 nM in cells; 50-100 nM against IL-1 and TNF-a production from LPS-stimulated human monocytes and the human monocyte cell line THP-1; 0.2-1.0 µM against platelet aggregation caused by collagen
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableY
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Hygroscopic Hygroscopic
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Global Trade Item Number
          Catalogue Number GTIN
          559395-10MG 04055977192575
          559395-1MG 04055977192568