Cellvento® CHO media have been developed for use with CHO suspension cell types such as CHO-S, CHO-DHFR- , CHO-K1, CHO-GS and CHOZN® cells, but may also be suitable for other cell lines. Available in powder and compacted forms, Cellvento® CHO formulations are chemically defined, of non-animal origin and lead to superior cell growth and productivity in batch, fed-batch or perfusion applications.
For fed-batch processes we aim to reduce the complexity of workflows by offering highly concentrated and one-part pH neutral feeds, allowing for a reduction in volume of feed added to replenish depleted nutrients, thereby increasing product yield. Highly concentrated, compacted format, easy to hydrate and product stability even at room temperature through Cellvento® ModiFeed Prime COMP allow for streamlined workflows.
Recommended basal media combinations are Cellvento® CHO media or EX-CELL® Advanced CHO Fed-batch medium as described within the product detail pages.
Cellvento® 4CHO-X has been designed to support high growth and viability, thus increasing cell biomass for cryopreservation or inoculation of another bioreactor. Cellvento® 4CHO-X supports seed train intensification at N-1 in perfusion, reaching robust growth at low CSPRs.
Use and Application | CHO-S Cell Lines | CHO-DHFR- and Slow Growing Cell Lines | CHO-K1 Cell Lines | CHOZN® Cell Lines |
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High concentrated single feed | Cellvento® ModiFeed Prime COMP | |||
Fed-batch system with high concentrated single feed | Cellvento® 4CHO COMP Medium | |||
Cellvento® 4Feed COMP | ||||
Enhanced Seed Train - N-1 Perfusion | Cellvento® 4CHO-X COMP Expansion Medium |
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Growth Media for Batch | Cellvento® CHO-110 Medium | |||
Production Media and Companion Feeds for Fed-Batch with Cys/Tyr supplementation | Cellvento® CHO-200 Medium | Cellvento® CHO-210 Medium | Cellvento® CHO-220 Medium | |
Cellvento® Feed-200 | Cellvento® Feed-210 | Cellvento® Feed-220 |