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484235 p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem

p-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NBT, Nitro BT

Primary Target: NOS
484235
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
298-83-9C₄₀H₃₀Cl₂N₁₀O₆

Products

Catalogue NumberPackaging Qty/Pack
484235-1GM Glass bottle 1 gm
484235-250MG Glass bottle 250 mg
Description
OverviewNADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).
Catalogue Number484235
Brand Family Calbiochem®
SynonymsNBT, Nitro BT
References
ReferencesPistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
Nichols, K., et al. 1992. Neuroscience 51, 791.
Nichols, K., et al. 1992. Neuroscience 51, 791.
Product Information
CAS number298-83-9
FormYellow crystalline solid
Hill FormulaC₄₀H₃₀Cl₂N₁₀O₆
Chemical formulaC₄₀H₃₀Cl₂N₁₀O₆
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Applicationp-Nitroblue Tetrazolium Chloride, CAS 298-83-9, is a NADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions.
Biological Information
Primary TargetNOS
Primary Target IC<sub>50</sub>3-4 µM
Purity≥98% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSXF8045000
Safety Information
R PhraseR: 20/21/22-68

Harmful by inhalation, in contact with skin and if swallowed.
Possible risks of irreversible effects.
S PhraseS: 22-26-36/37

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing and gloves.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
484235-1GM 07790788054755
484235-250MG 04055977200690

Documentation

p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

p-Nitroblue Tetrazolium Chloride - CAS 298-83-9 - Calbiochem Certificates of Analysis

TitleLot Number
484235

References

Reference overview
Pistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
Nichols, K., et al. 1992. Neuroscience 51, 791.
Nichols, K., et al. 1992. Neuroscience 51, 791.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-August-2008 RFH
SynonymsNBT, Nitro BT
DescriptionNADPH-diaphorase substrate that competitively inhibits nitric oxide synthase (IC50 = 3-4 µM). A well-known scavenger of superoxide anions. Useful as a substrate for alkaline phosphatase, often in conjunction with BCIP (Cat. No. 203788).
FormYellow crystalline solid
CAS number298-83-9
RTECSXF8045000
Chemical formulaC₄₀H₃₀Cl₂N₁₀O₆
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityMeOH or H₂O
Storage Protect from light
+2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage.
Toxicity Harmful
ReferencesPistelli, A., et al. 1994. Biochem. Pharmacol. 47, 1737.
De la Fuente, M., et al. 1993. Comp. Immunol. Microbiol. Infect. Dis. 16, 29.
Libon, C., et al. 1993. J. Leukoc. Biol. 53, 93.
Mittal, C.K. 1993. Biochem. Biophys. Res. Commun. 193, 126.
Nichols, K., et al. 1992. Neuroscience 51, 791.
Nichols, K., et al. 1992. Neuroscience 51, 791.