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GF315 VEGF165 Protein, Human Recombinant Animal Free

The Vascular endothelial growth factor (VEGF or VEGFA) is a potent mediator of both angiogenesis & vasculogenesis in the fetus & adult. Manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P15692 Entrez Gene Number: NM_001025366.1, NM_001025367.1, NM_001025368.1, NM_001025369.1, NM_001025370.1, NM_001033756.1, NM_003376.4
GF315
10 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF315
DescriptionVEGF165 Protein, Human Recombinant Animal Free
Alternate Names
  • Vascular Endothelial Growth Factor 165
  • VEGF-165
  • VEGF
  • Vascular Endothelial Growth Factor
  • VEGF-A
Background InformationVascular endothelial growth factor (VEGF or VEGFA) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
References
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
ApplicationThe Vascular endothelial growth factor (VEGF or VEGFA) is a potent mediator of both angiogenesis & vasculogenesis in the fetus & adult. Manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityMouse, Rat, Pig, Hamster, Trout, Green Algae, Sheep, Cow, Rabbit, Guinea Pig
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF315 04053252691515

Documentation

VEGF165 Protein, Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

VEGF165 Protein, Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
Recombinant Animal Free Human VEGF165 - 2137058 2137058
Recombinant Animal Free -2567134 2567134
Recombinant Animal Free -2621113 2621113
Recombinant Animal Free -2796267 2796267
Recombinant Animal Free Human VEGF165 - 2025430 2025430
Recombinant Animal Free Human VEGF165 - 2290996 2290996
Recombinant Animal Free Human VEGF165 - 2992843 2992843
Recombinant Animal Free Human VEGF165 - 3208789 3208789
Recombinant Animal Free Human VEGF165 - 3231927 3231927
Recombinant Animal Free Human VEGF165 - 3269454 3269454
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Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors