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662091 Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GST-Ubc5a (E2)

662091
  
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Overview

Replacement Information
Description
Overview

This product has been discontinued.



Recombinant, human ubiquitin conjugating enzyme 5a fused to GST and expressed in E. coli. E2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family which has been shown to play many important regulatory roles in inflammation and cancer.
Catalogue Number662091
Brand Family Calbiochem®
SynonymsGST-Ubc5a (E2)
References
ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
Ciechanover, A. 1994. Cell 79, 13.
Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
Product Information
FormLiquid
FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
662091 0

Documentation

Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli SDS

Title

Safety Data Sheet (SDS) 

Ubiquitin Conjugating Enzyme 5a, GST-Fusion, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
662091

References

Reference overview
Varshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
Ciechanover, A. 1994. Cell 79, 13.
Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.

Citations

Title
  • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision16-September-2008 RFH
    SynonymsGST-Ubc5a (E2)
    DescriptionE2s are a family of ubiquitin carrier proteins that transfer ubiquitin to the ε-lysine of proteins designated for degradation. UbcH5a is a human homolog of the yeast UBC4/5 family that has been shown to play many important regulatory roles in inflammation and cancer.
    FormLiquid
    FormulationIn 50 mM HEPES, 50 mM NaCl, 1 mM DTT, 10% glycerol, pH 7.6.
    Concentration Label Please refer to vial label for lot-specific concentration
    Purity≥95% by SDS-PAGE
    Storage Avoid freeze/thaw
    ≤ -70°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
    Toxicity Standard Handling
    ReferencesVarshavsky, A. 1997. Trends Biochem. Sci. 22, 383.
    Hochstrasser, M. 1996. Annu. Rev. Genet. 30, 405.
    Ciechanover, A. 1994. Cell 79, 13.
    Seufert, W., and Jentsch, S. 1990. EMBO J. 9, 543.
    Citation
  • Liguo Zhang, Kenneth P. Nephew and Patricia J. Gallagher. (2007) Regulation of death-associated protein kinase: stabilization by HSP90 heterocomplexes. Journal of Biological Chemistry 282, 11795-11804.
    		•