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557303 Rifampicin - CAS 13292-46-1 - Calbiochem

557303
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
13292-46-1C₄₃H₅₈N₄O₁₂

Products

Catalogue NumberPackaging Qty/Pack
557303-1GM 1 gm
557303-5GM Plastic ampoule 5 gm
Description
OverviewAntibiotic that specifically inhibits DNA-dependent RNA polymerase in bacteria by forming an inactive complex. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.
Catalogue Number557303
Brand Family Calbiochem®
SynonymsRifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV
References
ReferencesJin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.
Product Information
CAS number13292-46-1
FormBrownish-red to brick-red powder
Hill FormulaC₄₃H₅₈N₄O₁₂
Chemical formulaC₄₃H₅₈N₄O₁₂
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetDNA-dependent RNA polymerase in bacteria
Purity≥97% by Assay
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSVJ7000000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
557303-1GM 04055977267907
557303-5GM 07790788051488

Documentation

Rifampicin - CAS 13292-46-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Rifampicin - CAS 13292-46-1 - Calbiochem Certificates of Analysis

TitleLot Number
557303

References

Reference overview
Jin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.

Citations

Title
  • Asa Flanigan and Jeffrey F. Gardner. (2007) Interaction of the gifsy-1 xis protein with the gifsy-1 attP sequence. Journal of Bacteriology 189, 6303-6311.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision06-February-2019 JSW
    SynonymsRifampin, 3-(4-Methylpiperazinyliminomethyl)rifamycin SV
    DescriptionAntibiotic that specifically inhibits DNA-dependent bacterial RNA polymerase by forming an inactive complex with RNA polymerase. Does not affect mammalian RNA polymerase. Inhibits transcription by preventing the initial transcription complex from entering the elongation mode.
    FormBrownish-red to brick-red powder
    CAS number13292-46-1
    RTECSVJ7000000
    Chemical formulaC₄₃H₅₈N₄O₁₂
    Structure formulaStructure formula
    Purity≥97% by Assay
    SolubilityDMSO (25 mg/ml) or Methanol (25 mg/ml)
    Storage +15°C to +30°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). DMSO stock solutions are stable for up to 2 months at -20°C.
    Toxicity Harmful & Carcinogenic / Teratogenic
    Merck USA index14, 8216
    ReferencesJin, D.J. and Turnbough, Jr., C.L. 1994. J. Mol. Biol. 236, 72.
    Levin, M.E. and Hatfull, G.F. 1993. Mol. Microbiol. 8, 277.
    Wehrli, W., et al. 1968. Proc. Natl. Acad. Sci. USA 61, 667.
    Citation
  • Asa Flanigan and Jeffrey F. Gardner. (2007) Interaction of the gifsy-1 xis protein with the gifsy-1 attP sequence. Journal of Bacteriology 189, 6303-6311.