508514 Sigma-AldrichPsalmotoxin-1 - CAS 316808-68-1 - Calbiochem
A potent proton-gated sodium channel (ASIC1a) channel blocking neurotoxin (IC₅₀ = 0.9 nM) that can distinguish between the two ASIC1 splice variants, ASIC1a and ASIC1b.
More>> A potent proton-gated sodium channel (ASIC1a) channel blocking neurotoxin (IC₅₀ = 0.9 nM) that can distinguish between the two ASIC1 splice variants, ASIC1a and ASIC1b. Less<<Psalmotoxin-1 - CAS 316808-68-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: ASIC1a Inhibitor, Psalmotoxin 1
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Overview
Key Spec Table
| CAS # | Empirical Formula |
|---|---|
| 316808-68-1 | C₂₀₀H₃₁₂N₆₂O₅₇S₆ |
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 5.08514.0001 | Glass bottle | 20 μg |
| References | |
|---|---|
| References | Qadri, Y. J. et al. 2009. J. Biol. Chem. 284, 17625. M. Mazzuca, et al. 2007. Nat Neurosci. 10, 943. Escoubas, P. et al. 2000. J. Biol. Chem. 275, 25116. |
| Product Information | |
|---|---|
| CAS number | 316808-68-1 |
| Form | Colorless semi-solid to viscous liquid |
| Hill Formula | C₂₀₀H₃₁₂N₆₂O₅₇S₆ |
| Chemical formula | C₂₀₀H₃₁₂N₆₂O₅₇S₆ |
| Hygroscopic | Hygroscopic |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | ASIC1a |
| Primary Target IC<sub>50</sub> | 0.9 nM |
| Purity | ≥94% by HPLC |
| Physicochemical Information | |
|---|---|
| Peptide Sequence | EDCIPKWKGCVNRHGDCCEGLECWKRRRSFEVCVPKTPKT (disulfide bond 3-18, 10-23, 17-33) |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 5.08514.0001 | 04055977262056 |