Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

5291 Polymyxin B Sulfate - CAS 1405-20-5 - Calbiochem

Polymyxin B Sulfate, CAS 1405-20-5, is an antibiotic that is effective against Gram-positive bacteria. Inhibits phospholipid-sensitive Ca2+-dependent protein kinases.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Aerosporin

5291
  
Purchase on Sigma-Aldrich

Overview

Key Spec Table

CAS #
1405-20-5
Description
OverviewAn antibiotic that inhibits phospholipid-sensitive Ca2+-dependent protein kinases. Mixture of polymyxin B1 sulfate and polymyxin B2 sulfate. Binds to cell wall and makes it more permeable, causing fluid uptake. Effective against Gram-negative bacteria.
Catalogue Number5291
Brand Family Calbiochem®
SynonymsAerosporin
References
ReferencesLucas, M., et al. 1994. Biochem. Pharmacol. 47, 667.
Ngezahayo, A. and Kolb, H.A. 1993. Pflugers Arch. 422, 413.
Kubo, M. and Okada, Y. 1992. J. Physiol. 456, 351.
Strasser, S.H., et al. 1992. Circ. Res. 70, 1304.
Hegemann, L., et al. 1991. Eur. J. Pharmacol. 207, 17.
Inaba, H. and Filkins, J.P. 1991. Am. J. Physiol. 261, R26.
Marra, M.N., et al. 1990. J. Immunol. 144, 662.
Product Information
CAS number1405-20-5
FormWhite to off-white solid
Quality LevelMQ200
Biological Information
Biological activityPotency: ≥7500 IU/mg
Primary TargetPhospholipid sensitive Ca2+ dependent protein kinases
Safety Information according to GHS
RTECSTR1150000
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 36

Wear suitable protective clothing.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 year at -20°C.
Global Trade Item Number
Catalogue Number GTIN
5291 0