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14-508M PKCµ Protein, active, 250 µg

Active, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.

PKCµ Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-508M
250 µg  Also available in 10 μg size (cat#14-508) and in bulk (cat# 14-508-K).
Purchase on Sigma-Aldrich

Overview

Description
Catalogue Number14-508M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPKCµ Protein, active, 250 µg
OverviewN-terminal His6-tagged recombinant, full length, human PKCμ.
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal His6-tagged recombinant, full length, human PKCμ. For use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceHuman PKCμ expressed in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryMembers of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]
Gene Symbol
  • PRKD1
  • PKD
  • PKCM
  • nPKC-mu
  • PRKCM
  • PKC-mu
  • nPKC-D1
  • PKC-MU
  • PKD1
Protein TargetPKCµ
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q15139 # This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.
SIZE: 912 amino acids; 101888 Da
SUBUNIT: Interacts via its N-terminal region with CENTA1.
PTM: Autophosphorylated (By similarity).
SIMILARITY: SwissProt: Q15139 ## Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. & Contains 1 PH domain. & Contains 2 phorbol-ester/DAG-type zinc fingers. & Contains 1 protein kinase domain.
Molecular Weight105kDa
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of MAPKAP Kinase 2 Substrate Peptide
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-508) and in bulk (cat# 14-508-K).
Global Trade Item Number
Catalogue Number GTIN
14-508M 04053252278686