Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

539563 PKCδ Peptide Substrate

539563
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Overview

This product has been discontinued.





A highly specific substrate for the protein kinase Cδ isozyme (PKCδ; Km = 22.9 µM). The sequence corresponds to amino acid residues 422 - 443 of murine εEF-1α containing Thr431, which is phosphorylated by PKCδ. Arg429 is essential for recognition of this peptide as PKCδ substrate.
Catalogue Number539563
Brand Family Calbiochem®
SynonymsRFAVRDMRQTVAVGVIKAVDKK, Protein Kinase Cδ Peptide Substrate
References
ReferencesKielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.
Product Information
ATP CompetitiveN
FormLyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₀₉H₁₉₁N₃₅O₂₉S
Chemical formulaC₁₀₉H₁₉₁N₃₅O₂₉S
Hygroscopic Hygroscopic
ReversibleN
Applications
Biological Information
Primary TargetA highly specific substrate for the protein kinase Cδ isozyme
Primary Target IC<sub>50</sub>Km = 22.9 µM for protein kinase Cδ isozyme (PKCδ)
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceH-Arg-Phe-Ala-Val-Arg-Asp-Met-Arg-Gln-Thr-Val-Ala-Val-Gly-Val-Ile-Lys-Ala-Val-Asp-Lys-Lys-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
539563 0

Documentation

PKCδ Peptide Substrate SDS

Title

Safety Data Sheet (SDS) 

PKCδ Peptide Substrate Certificates of Analysis

TitleLot Number
539563

References

Reference overview
Kielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-September-2008 RFH
SynonymsRFAVRDMRQTVAVGVIKAVDKK, Protein Kinase Cδ Peptide Substrate
DescriptionA highly specific substrate for the protein kinase Cδ isozyme (PKCδ; Km = 22.9 µM). The sequence corresponds to residues 422-443 of murine eEF-1α, containing Thr431, which is phosphorylated by PKCδ.
FormLyophilized solid
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₁₀₉H₁₉₁N₃₅O₂₉S
Peptide SequenceH-Arg-Phe-Ala-Val-Arg-Asp-Met-Arg-Gln-Thr-Val-Ala-Val-Gly-Val-Ile-Lys-Ala-Val-Asp-Lys-Lys-OH
Purity≥95% by HPLC
SolubilityDMSO or H₂O (25 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesKielbassa, K., et al. 1995. J. Biol. Chem. 270, 6156.