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495455 Oligomycin - CAS 1404-19-9 - Calbiochem

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Oligomycin - CAS 1404-19-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Primary Target: Membrane-bound mitochondrial ATPase (F1)
495455
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
1404-19-9C₄₅H₇₄O₁₁

Products

Catalogue NumberPackaging Qty/Pack
495455-10MG Plastic ampoule 10 mg
Description
OverviewA mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
Catalogue Number495455
Brand Family Calbiochem®
References
ReferencesWolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
Product Information
CAS number1404-19-9
ATP CompetitiveN
FormWhite solid
Hill FormulaC₄₅H₇₄O₁₁
Chemical formulaC₄₅H₇₄O₁₁
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMembrane-bound mitochondrial ATPase (F1)
Purity≥90% by HPLC (mixture of A, B, and C isomers)
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSRK3325000
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
495455-10MG 04055977199734

Documentation

Oligomycin - CAS 1404-19-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Oligomycin - CAS 1404-19-9 - Calbiochem Certificates of Analysis

TitleLot Number
495455

References

Reference overview
Wolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision11-July-2012 JSW
DescriptionA mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.
FormWhite solid
CAS number1404-19-9
RTECSRK3325000
Chemical formulaC₄₅H₇₄O₁₁
Structure formulaStructure formula
Purity≥90% by HPLC (mixture of A, B, and C isomers)
SolubilityEthanol (250 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.
Toxicity Irritant
Merck USA index14, 6833
ReferencesWolvetang, E.J., et al. 1994. FEBS Lett. 339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther. 264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett. 315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta 1141, 231.