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492029 NRG1-β1/HRG1-β1 EGF Domain, Human, Recombinant

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
492029
  
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Overview

Key Spec Table

Purity
≥97% by SDS-PAGE
Description
Overview

This product has been discontinued.



Recombinant, human neuregulin 1-β1/heregulin 1-β1 epidermal growth factor-like domain (NRG1-β1/HRG1-β1 EGF Domain), consisting of amino acids 176-246 and expressed in E. coli. All NRG1 isoforms contain an EGF-like domain that is required for binding directly to the ErbB3 or ErbB4 receptor tyrosine kinases.
Catalogue Number492029
Brand Family Calbiochem®
References
ReferencesBuonanno, A., and Fischbach, G.D. 2001. Curr. Opin. Neurobiol. 11, 287.
Adlkofer, K. and Lai, C. 2000. Glia 29, 104.
Garratt, A.N. et al. 2000. BioEssays 22, 987.
Karey, K.P., et al. 1988. Cancer Res. 48, 4083.
Product Information
FormLyophilized
FormulationLyophilized from 0.2 µm filtered acetonitrile, TFA, BSA.
Quality LevelMQ100
Biological Information
Biological activityED₅₀ = 0.06-0.3 ng/ml as measured in a serum-free proliferation assay using MCF-7 human breast adenocarcinoma cells.
Purity≥97% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: ≤1.0 EU/µg protein
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
492029 0