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FCMAB188F Sigma-AldrichMilli-Mark™ Anti-CD24-FITC Antibody, clone SN3

Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

SDS
CoA

Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P25063

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Overview

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Key Spec Table

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	FC	M	FITC	Monoclonal Antibody

Description
Catalogue Number	FCMAB188F
Trade Name	Milli-Mark
Description	Milli-Mark™ Anti-CD24-FITC Antibody, clone SN3
Alternate Names	Signal transducer CD24 Small cell lung carcinoma cluster 4 antigen
Background Information	The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002). CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).

Product Information
Format	FITC
Control	PBMCs
Presentation	Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality Level	MQ100

Applications
Application	Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.
Key Applications	Flow Cytometry

Biological Information
Immunogen	Isolated membrane fraction of the pre-B leukemic cell line NALM-1.
Clone	SN3
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Mouse
Specificity	Antibody recognizes Human CD24 antigen.
Isotype	IgG1κ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_037362.1
Purification Method	Protein A Purfied
UniProt Number	P25063
Molecular Weight	35-45 kDa (Turni, 2002)

Product Usage Statements
Quality Assurance	Evaluated by flow cytometry using human PBMCs
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Packaging Information
Material Size	100 tests

Global Trade Item Number
Catalogue Number	GTIN
FCMAB188F	04053252289156

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