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454565 Methyl Arachidonyl Fluorophosphonate - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: MAFP, cPLA2α Inhibitor III

Primary Target: calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
454565
  
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₁H₃₆FO₂P
Description
Overview

This product has been discontinued.



A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not of secretory PLA2.
Catalogue Number454565
Brand Family Calbiochem®
SynonymsMAFP, cPLA2α Inhibitor III
References
ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
Product Information
ATP CompetitiveN
FormLiquid
FormulationIn methyl acetate.
Hill FormulaC₂₁H₃₆FO₂P
Chemical formulaC₂₁H₃₆FO₂P
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetcalcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
454565 0

Documentation

Methyl Arachidonyl Fluorophosphonate - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Methyl Arachidonyl Fluorophosphonate - Calbiochem Certificates of Analysis

TitleLot Number
454565

References

Reference overview
Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-August-2008 RFH
SynonymsMAFP, cPLA2α Inhibitor III
DescriptionA selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2) but not secretory PLA2.
FormLiquid
FormulationIn methyl acetate.
Chemical formulaC₂₁H₃₆FO₂P
Structure formulaStructure formula
Purity≥98% by TLC
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsPrior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.
Toxicity Standard Handling
ReferencesBalsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55.