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444241 MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem

The MMP-2/MMP-9 Inhibitor I, also referenced under CAS 193807-58-8, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid

Primary Target: MMP-2, MMP-9
444241
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
193807-58-8C₂₁H₁₉NO₄S

Products

Catalogue NumberPackaging Qty/Pack
444241-5MG Plastic ampoule 5 mg
Description
OverviewA potent inhibitor of MMP-2 (IC50 = 310 nM) and MMP-9 (IC50 = 240 nM). Orally active in animal models of tumor growth and metastasis.
Catalogue Number444241
Brand Family Calbiochem®
Synonyms(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
References
ReferencesTamura, Y., et al. 1998. J. Med. Chem. 41, 640.
Product Information
CAS number193807-58-8
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₁H₁₉NO₄S
Chemical formulaC₂₁H₁₉NO₄S
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMMP-2, MMP-9
Primary Target IC<sub>50</sub>310 nM and 240 nM against MMP-2 and MMP-9
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
444241-5MG 07790788056384

Documentation

MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

MMP-2/MMP-9 Inhibitor I - CAS 193807-58-8 - Calbiochem Certificates of Analysis

TitleLot Number
444241

References

Reference overview
Tamura, Y., et al. 1998. J. Med. Chem. 41, 640.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-April-2011 RFH
Synonyms(2R)-2-[(4-Biphenylylsulfonyl)amino]-3-phenylpropionic Acid
DescriptionA potent inhibitor of MMP-2 (gelatinase A; IC50 = 310 nM) and MMP-9 (gelatinase B; IC50 = 240 nM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number193807-58-8
Chemical formulaC₂₁H₁₉NO₄S
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml)
Storage -20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesTamura, Y., et al. 1998. J. Med. Chem. 41, 640.