Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

407715 Interleukin-13, Human, Recombinant, E. coli

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: rhIL-13

407715
  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Overview

This product has been discontinued.



Recombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. A potent regulator of STAT6 and JAK3 in NK and T cells. Regulates inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
Catalogue Number407715
Brand Family Calbiochem®
SynonymsrhIL-13
References
ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
Saura, M., et al. 1996. Biochem. J. 313, 641.
Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
Minty, A., et al. 1993. Nature 362, 248.
Product Information
CAS number148157-34-0
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, pH 7.4.
Quality LevelMQ100
Applications
Biological Information
Biological activityED₅₀ = 0.5-2.5 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
Purity≥95% by SDS-PAGE
Physicochemical Information
ContaminantsEndotoxin: <1.0 EU/µg IL-13
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
407715 0

Documentation

Interleukin-13, Human, Recombinant, E. coli SDS

Title

Safety Data Sheet (SDS) 

Interleukin-13, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
407715

References

Reference overview
Yu, C.R., et al. 1998. J. Immunol. 161, 218.
Saura, M., et al. 1996. Biochem. J. 313, 641.
Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
Minty, A., et al. 1993. Nature 362, 248.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision14-December-2018 JSW
SynonymsrhIL-13
DescriptionRecombinant, human interleukin-13 expressed in E. coli. Pleiotropic cytokine that shares many of the properties of IL-4. Exhibits IL-4-like activities on monocytes/macrophages and human B cells but has no effect on T cells. Potent regulator of inflammatory and immune responses. Inhibits inducible nitric oxide synthase in human mesangial cells.
FormLyophilized
FormulationLyophilized from sterile-filtered PBS, pH 7.4.
CAS number148157-34-0
Purity≥95% by SDS-PAGE
ContaminantsEndotoxin: <1.0 EU/µg IL-13
Biological activityED₅₀ = 0.5-2.5 ng/ml as measured in a cell proliferation assay using a human factor-dependent cell line, TF-1
SolubilityReconstitute to a concentration of ≥5 µg/ml with sterile PBS.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C. Avoid freeze/thaw cycles of solutions.
Toxicity Standard Handling
ReferencesYu, C.R., et al. 1998. J. Immunol. 161, 218.
Saura, M., et al. 1996. Biochem. J. 313, 641.
Xi, X., et al. 1995. Br. J. Haematol. 90, 921.
Zurawski, G., and DeVries, J.E. 1994. Stem Cells 12, 169.
McKenzie, A.N.J., et al. 1993. Proc. Natl. Acad. Sci. USA 90, 3735.
Minty, A., et al. 1993. Nature 362, 248.