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203389 InSolution™Blebbistatin, Racemic - Calbiochem

203389
Purchase on Sigma-Aldrich

Overview

Key Spec Table

Empirical Formula
C₁₈H₁₆N₂O₂

Products

Catalogue NumberPackaging Qty/Pack
203389-5MG Plastic ampoule 5 mg
Description
Catalogue Number203389
Brand Family Calbiochem®
References
ReferencesShu, S., et al. 2005. Proc. Natl. Acad. Sci. USA 102, 1472.
Kovacs, M., et al. 2004. J. Biol. Chem. 279, 35557.
Straight, A.F., et al. 2003. Science 299, 1743.
Cheung, A., et al. 2001. Mol. Biol. Cell Suppl. 12, 271a.
Product Information
ATP CompetitiveN
FormLiquid
FormulationA 50 mM (5 mg/342 µl) solution of (±)-Blebbistatin (Cat. No. 203390) in 90% DMSO.
Hill FormulaC₁₈H₁₆N₂O₂
Chemical formulaC₁₈H₁₆N₂O₂
Hygroscopic Hygroscopic
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationInSolution™Blebbistatin, Racemic, is a 50 mM in 90% DMSO. A cell-permeable, selective, and reversible inhibitor of nonmuscle myosin II. Blocks cell blebbing and disrupts cell migration & cytoKinesis.
Biological Information
Primary TargetATPase
Primary Target IC<sub>50</sub><100 µM inhibiting the ATPase and gliding motility of human platelets
Purity≥97% by HPLC
Physicochemical Information
Cell permeableY
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Harmful & Carcinogenic / Teratogenic
Storage -20°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Global Trade Item Number
Catalogue Number GTIN
203389-5MG 04055977221251