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508436 InSolution™ AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem

A 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride in H₂O.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: AEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl

Primary Target: serine proteases
508436
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
30827-99-7C₈H₁₀FNO₂S • HCl

Products

Catalogue NumberPackaging Qty/Pack
5.08436.0001 Glass bottle 50 mg
Description
Catalogue Number508436
Brand Family Calbiochem®
SynonymsAEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl
References
ReferencesCitron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
Product Information
CAS number30827-99-7
FormLiquid
FormulationA 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride (Cat. No. 101500) in H₂O.
Hill FormulaC₈H₁₀FNO₂S • HCl
Chemical formulaC₈H₁₀FNO₂S • HCl
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetserine proteases
Purity≥97% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 1 year at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
5.08436.0001 04055977261950

Documentation

InSolution™ AEBSF, Hydrochloride - CAS 30827-99-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Citron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision10-January-2014 JSW
SynonymsAEBSF, HCl InSolution, 4-(2-Aminoethyl)benzenesulfonylfluoride, HCl, 4-(2-Aminoethyl)benzene-1-sulfonylfluoride, HCl
DescriptionSpecific, irreversible inhibitor of serine proteases. Inhibits chymotrypsin, kallikrein, plasmin, thrombin, trypsin, and related thrombolytic enzymes. Stable, nontoxic alternative to PMSF (Cat. No. 52332) and DFP (Cat. No. 30967). A β-secretase inhibitor that inhibits β-amyloid peptide (Aβ) production and enhances amyloid precursor protein (sAPPUα) secretion in several cell lines at millimolar concentrations. Use at the same molar concentrations (0.1-1.0 mM) as PMSF for most applications.
FormLiquid
FormulationA 50 mM (50 mg/4.17 ml) sterile-filtered solution of AEBSF, Hydrochloride (Cat. No. 101500) in H₂O.
Intert gas (Yes/No) Packaged under inert gas
CAS number30827-99-7
Chemical formulaC₈H₁₀FNO₂S • HCl
Structure formulaStructure formula
Purity≥97% by HPLC
Storage Protect from light
Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 1 year at -20°C.
Toxicity Standard Handling
ReferencesCitron, M., et al. 1996. Neuron 17, 171.
Ohkubo, I., et al. 1994. J. Biochem. 116, 1182.
Mintz, G.R. 1993. BioPharm. 6, 34.
Lawson, W.B., et al. 1982. Folia Haematol. 109, 52.
Markwardt, F., et al. 1974. Biochem. Pharmacol. 23, 2247.
Markwardt, F., et al. 1973. Thromb. Res. 2, 343.
Baker, B.R., and Cory, M. 1971. J. Med. Chem. 14, 119.