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GF338 IL-6,
Human Recombinant Animal Free

IL-6,
Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P05231
GF338
20µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

SourcePurity
Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue NumberGF338
DescriptionIL-6,
Human Recombinant Animal Free
Alternate Names
  • Interleukin-6
  • IL6
Background InformationIL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through
the IL-6 receptor system that consists of two chains, IL-6R and gp130. Murine IL-6 is inactive on human cells, while both
human and murine are equally active on murine cells.
Recombinant human IL-6 is a 20.9 kDa protein containing 184 amino acid residues.
References
Product Information
PresentationProduct is presented in 10mM Sodium Phosphate, pH 7.5 and is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
Biological Information
PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
SourceProtein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceDetermined by its ability to stimulate the proliferation of mouse B9 cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-0.5 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Packaging Information
Material Size20µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
GF338 04053252978982

Documentation

IL-6,
Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

IL-6,
Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
IL-6, Human Recombinant Animal Free - Q2436472 Q2436472
IL-6, -2594865 2594865
IL-6, -2636732 2636732
IL-6, Human Recombinant Animal Free 2468792
IL-6, Human Recombinant Animal Free - 3385864 3385864
IL-6, Human Recombinant Animal Free - 3464587 3464587
IL-6, Human Recombinant Animal Free - 3532436 3532436
IL-6, Human Recombinant Animal Free - 3537639 3537639
IL-6, Human Recombinant Animal Free - 3588024 3588024
IL-6, Human Recombinant Animal Free - 3670797 3670797
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Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors