345885 Sigma-AldrichGGTI-2147 - CAS 191102-87-1 - Calbiochem
A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I).
More>> A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). Less<<Synonyms: 4-[[N-(Imidazol-4-yl)methyleneamino]-2-(1-naphthyl)benzoyl]leucine methyl ester
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Overview
Key Spec Table
CAS # | Empirical Formula |
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191102-87-1 | C₂₈H₃₀N₄O₃ |
Products
Catalogue Number | Packaging | Qty/Pack | |
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345885-250UG | Plastic ampoule | 250 μg |
References | |
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References | Bernot, D., et al. 2003. J. Cardiovasc. Pharmacol. 41, 316. Vasudevan, A., et al. 1999. J. Med. Chem. 42, 1333. |
Product Information | |
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CAS number | 191102-87-1 |
ATP Competitive | N |
Form | Off-white solid |
Hill Formula | C₂₈H₃₀N₄O₃ |
Chemical formula | C₂₈H₃₀N₄O₃ |
Hygroscopic | Hygroscopic |
Reversible | N |
Structure formula Image | |
Quality Level | MQ100 |
Biological Information | |
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Primary Target | GGTase-I |
Primary Target IC<sub>50</sub> | 500 nM in blocking the geranyl-geranylation of Rap1A |
Purity | ≥95% by HPLC |
Physicochemical Information | |
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Cell permeable | Y |
Packaging Information | |
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Packaged under inert gas | Packaged under inert gas |
Global Trade Item Number | |
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Catalogue Number | GTIN |
345885-250UG | 04055977214529 |