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219419 Cathepsin Inhibitor III - Calbiochem

219419
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Overview

Key Spec Table

Empirical Formula
C₂₇H₂₇N₃O₇

Products

Catalogue NumberPackaging Qty/Pack
219419-1MG Plastic ampoule 1 mg
Description
OverviewCysteine protease inhibitor. Selectively inhibits cathepsin B (k2/Ki = 1 x 104 M-1 sec-1), cathepsin L (k2/Ki = 1.5 x 105 M-1 sec-1), cathepsin S (k2/Ki = 6.6 x 104 M-1 sec-1), and papain (k2/Ki = 1 x 103 M-1 sec-1).
Half-life in buffered solution (pH 5-9) = 37 h (30°C); 300 h (0°C).
Catalogue Number219419
Brand Family Calbiochem®
SynonymsZ-FG-NHO-BzOME
References
ReferencesDemuth, H.-U., et al. 1996. Biochim. Biophys. Acta 1295, 179.
Brömme, D., and Demuth, H.-U. 1994. Methods Enzymol. 244, 671.
Product Information
ATP CompetitiveN
FormWhite solid
Hill FormulaC₂₇H₂₇N₃O₇
Chemical formulaC₂₇H₂₇N₃O₇
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary Targetcathepsin B
Primary Target K<sub>i</sub>k₂/Ki = 1 x 10⁴ M⁻¹ sec⁻¹
Purity>90% by HPLC
Physicochemical Information
Cell permeableN
Peptide SequenceZ-Phe-Gly-NHO-Bz-pOMe
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Protect from Light Protect from light
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalogue Number GTIN
219419-1MG 04055977218336