218747 Caspase-3 Inhibitor II, Biotin Conjugate
Recommended Products
Overview
| Replacement Information |
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| Description | |
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| Overview | Biotinylated derivative of Caspase-3 inhibitor II (Cat. No. 264155) that has been esterified to increase cell permeability. Also inhibits caspase-6, caspase-7, and caspase-10. Can be used to purify caspase-3 from cell lysates. The addition of esterase will enhance inhibitory activity in cell-free systems. |
| Catalogue Number | 218747 |
| Brand Family | Calbiochem® |
| Synonyms | Biotin-X-DEVD-FMK |
| References | |
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| References | Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Nicholson, D.W., et al. 1995. Nature 376, 37. |
| Product Information | |
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| Form | Brown solid |
| Hill Formula | C₃₈H₅₉FN₇O₁₃S |
| Chemical formula | C₃₈H₅₉FN₇O₁₃S |
| Reversible | N |
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| Biological Information | |
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| Primary Target | caspase-6, caspase-7 |
| Purity | ≥95% by TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Biotin-X-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-CH₂F* (X = linker) |
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| Safety Information according to GHS |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 218747 | 0 |
Documentation
Caspase-3 Inhibitor II, Biotin Conjugate Certificates of Analysis
| Title | Lot Number |
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| 218747 |
References
| Reference overview |
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| Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Nicholson, D.W., et al. 1995. Nature 376, 37. |