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SCT094 BioTracker NIR FolateReceptor Live Cell Dye

Near-Infrared probe for detection and visualization of folate receptors in vivo.

SCT094
1 mg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT094
DescriptionBioTracker NIR FolateReceptor Live Cell Dye
OverviewFolate receptors (FRs) are membrane bound surface proteins involved in folic acid uptake. FRs are frequently overexpressed in a large number of solid tumors including cancers of the ovary, breast and lung. FRs are attractive candidates for cancer imaging and targeted therapies.

BioTracker NIR Folate Receptor Live Cell Dye is a near-infrared (NIR) fluorescent probe for the detection of folate receptors in vivo. This probe exhibits very low background fluorescence and high tumor-to-background ratio in FR-expressing tumor-bearing mice within 30 min (1).

Reference:
1. Numasawa, Koji, et al. "A Fluorescent Probe for Rapid, High‐Contrast Visualization of Folate‐Receptor‐Expressing Tumors In Vivo." Angewandte Chemie International Edition 59.15 (2020): 6015-6020.
Alternate Names
  • Live Cell Imaging Probe
References
Product Information
Detection methodFluorescence
PresentationLyophilized. Green solid.
Applications
ApplicationNear-Infrared probe for detection and visualization of folate receptors in vivo.
Biological Information
Molecular Weight1196.30
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity ≥ 95% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT094 04065265944465

Documentation