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SCT050 BioTracker DCM-Bgal Live Cell Dye

Near-Infrared live cell imaging dye for visualization of beta-Galactosidase activity, an important marker for cell senescence and primary ovarian cancers.

SCT050
1 mg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue NumberSCT050
DescriptionBioTracker DCM-Bgal Live Cell Dye
OverviewThe BioTracker DCM-Bgal live cell dye is a ratiometric near-infrared (NIR) dye for the real-time fluorescent quantification of beta-galatosidase (ß-gal) enzyme activity in vitro, in vivo and in situ.

ß-galactosidase is an important marker for cell senescence and primary ovarian cancers. BioTracker DCM-Bgal live cell dye has light-up ratiometric NIR fluorescence with
large Stokes shift, high photostability than commercial ICG, and pH independency under the physiological range, allowing for the real-time
evaluation of β-gal activity. DCM-βgal displays higher affinity for β-gal
than commercial X-gal and much faster response to β-gal than
the previously reported FDG.

Spectral Properties
NIR fluorescence images obtained from 605 to 725 nm, λex = 560 nm

References
Gu K et al. Real-Time Tracking and In Vivo Visualization of ß-galactosidase Activity in Colorectal Tumor with a ratiometric Near-Infrared Fluorescent Probe. J. Am. Chem. Soc. 2016, 138, 5334-5340.
Alternate Names
  • Live cell imaging probe
References
Product Information
Detection methodFluorescence
PresentationLyophilized
Applications
ApplicationNear-Infrared live cell imaging dye for visualization of beta-Galactosidase activity, an important marker for cell senescence and primary ovarian cancers.
Key Applications
  • Cell Based Assays
  • Fluorescence
Application NotesLive cell fluorescent imaging
Biological Information
ConcentrationPlease refer to lot specific datasheet.
Molecular Weight474.5 g/mol
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssurancePurity: ≥ 98% confirmed by HPLC. LC-MS and HNMR confirms structure. Molar Mass: 474.5 g/mol
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore BioTracker DCM-Bgal Live Cell Dye at -20°C, desiccate and protect from light
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
Packaging Information
Material Size1 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
SCT050 04061841072768