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178496 Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem

The Apoptosis Activator VI, CD437/AHPN, also referenced under CAS 125316-60-1, modulates Apoptosis. This small molecule/inhibitor is primarily used for Cancer applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid

178496
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
125316-60-1C₂₇H₂₆O₃

Products

Catalogue NumberPackaging Qty/Pack
178496-5MG Plastic ampoule 5 mg
Description
OverviewA cell-permeable retinoid-related molecule that induces tumor growth arrest and apoptosis. The exact molecular basis of the underlying mechanism(s) is not yet well understood, however, studies using ovarian adenocarcinoma cells have shown that CD437/AHPN effectively functions as an ER stress inducer.
Catalogue Number178496
Brand Family Calbiochem®
Synonyms6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid
References
ReferencesWatanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.
Product Information
CAS number125316-60-1
FormOff-white solid
Hill FormulaC₂₇H₂₆O₃
Chemical formulaC₂₇H₂₆O₃
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 62-63

Possible risk of impaired fertility.
Possible risk of harm to the unborn child.
S PhraseS: 22-24/25-36/37/39

Do not breathe dust.
Avoid contact with skin and eyes.
Wear suitable protective clothing, gloves and eye/face protection.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
178496-5MG 04055977204810

Documentation

Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Apoptosis Activator VI, CD437/AHPN - CAS 125316-60-1 - Calbiochem Certificates of Analysis

TitleLot Number
178496

References

Reference overview
Watanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-February-2008 JSW
Synonyms6-(3-(1-Adamantyl)-4-hydroxyphenyl)-2-naphthalene carboxylic acid
DescriptionA cell-permeable retinoid-related molecule that induces tumor growth arrest and apoptosis. The exact molecular basis of the underlying mechanism(s) is not yet well understood, however, studies using ovarian adenocarcinoma cells have shown that CD437/AHPN effectively functions as an ER stress inducer.
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number125316-60-1
Chemical formulaC₂₇H₂₆O₃
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (39 mg/ml) or Ethanol (39 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 months at -20°C.
Toxicity Carcinogenic / Teratogenic
ReferencesWatanabe, Y., et al. 2008. Biochem. Biophys. Res. Comm. 366, 840.
Holmes, W.F., et al. 2004. J. Cell. Physiol. 199, 317.
Zhao, X., and Spanjaard, R.A. 2003. J. Biomed. Sci. 10, 44.