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MABC710 Anti-TGFBR3, clone 1C5H11 Antibody

MABC710
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, MWB, FC, ELISAMAscitesMonoclonal Antibody
Description
Catalogue NumberMABC710
DescriptionAnti-TGFBR3, clone 1C5H11 Antibody
Alternate Names
  • Transforming growth factor beta receptor type 3
  • TGF-beta receptor type 3
  • TGFR-3
  • Betaglycan
  • Transforming growth factor beta receptor III
  • TGF-beta receptor type III
  • TGFBR3
Background InformationTransforming growth factor beta receptor type 3 (TGF-beta receptor type 3 or TGFR-3), also known as Betaglycan or Transforming growth factor beta receptor III (TGF-beta receptor type III), and encoded by the gene name TGFBR3, is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. TGFBR3 is extensively modified by glycosaminoglycan groups (GAG).
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-TGFBR3, clone 1C5H11 Antibody is an antibody against TGFBR3 for use in western blotting, flow cytometry & ELISA.
Key Applications
  • Western Blotting
  • Flow Cytometry
  • ELISA
Application NotesFlow Cytometry Analysis: A 1:200-1:400 dilution from a representative lot detected TGFBR3 in MOLT4 cells.

ELISA: A representative lot was used on Control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).



Biological Information
ImmunogenPurified recombinant fragment of human TGFBR3 expressed in E. Coli
Clone1C5H11
HostMouse
IsotypeIgG2b
Species Reactivity
  • Human
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • TGFBR3
Purification MethodUnpurified
UniProt Number
Molecular Weight~93 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.

Western Blotting Analysis: A 1:500-1:2,000 dilution of this antibody detected TGFBR3 in Jurkat, HeLa, MCF-7, F9, SK-N-SH and NIH/3T3 cell lysates.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABC710 04053252957239

Documentation

Anti-TGFBR3, clone 1C5H11 Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-TGFBR3, clone 1C5H11 Antibody Certificates of Analysis

TitleLot Number
Anti-TGFBR3, clone 1C5H11 - QVP1312040 QVP1312040
Anti-TGFBR3, clone 1C5H11 - VP1408061 VP1408061
Anti-TGFBR3, clone 1C5H11 - VP1711172 VP1711172
Anti-TGFBR3, clone 1C5H11 - VP2203030 VP2203030
Anti-TGFBR3, clone 1C5H11 -VP1505226 VP1505226
Anti-TGFBR3, clone 1C5H11 -VP1608036 VP1608036
Anti-TGFBR3, clone 1C5H11 Monoclonal Antibody VP1702021
Anti-TGFBR3, clone 1C5H11 Monoclonal Antibody VP1808171