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FCMAB117P Anti-SSEA-1 Antibody, clone MC-480, PE conjugate

FCMAB117P
100 tests  
Purchase on Sigma-Aldrich

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Overview

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
M, R, HIHC, IP, IF, FCMPhycoerythrinMonoclonal Antibody
Description
Catalogue NumberFCMAB117P
DescriptionAnti-SSEA-1 Antibody, clone MC-480, PE conjugate
Alternate Names
  • SSEA-1
Background InformationSSEA-1 is expressed on the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG). No immunoreactivity is evident with undifferentiated human EC and ES cells. Expression of SSEA-1 is down regulated following differentiation of murine EC and ES cells. In contrast, the differentiation of human EC and ES cells is characterized by an increase in SSEA-1 expression.
Product Information
FormatPhycoerythrin
Control
  • Mouse embryonic Stem Cells
PresentationPurified mouse monoclonal IgM conjugated to PE fluorochrome in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationAnti-SSEA-1 Antibody, clone MC-480, PE conjugate is an antibody against SSEA-1 for use in IH, IP, IF, FC.
Key Applications
  • Immunohistochemistry
  • Immunoprecipitation
  • Immunofluorescence
  • Flow Cytometry
Biological Information
ImmunogenF9 tetracarcinoma stem cells (X-irradiated).
EpitopeMC-480
CloneMC-480
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostMouse
SpecificityThis antibody reacts with the Stage-specific embryonic antigen-1 (SSEA-1) that is expressed upon the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG).
IsotypeIgM
Species Reactivity
  • Mouse
  • Rat
  • Human
Species Reactivity NoteThis antibody reacts with the Stage-specific embryonic antigen-1 (SSEA-1) that is expressed upon the surface of early mouse embryos, murine embryonal carcinoma cells (EC), murine embryonic stem cells (ES) and murine & human germ cells (EG).
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryFUT4 catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). It has been detected in human embryos (5-10 weeks) suggesting a role in development.
Gene Symbol
  • FUT4
  • ELFT
  • FCT3A
  • Fuc-TIV
  • 1,3fucosyltransferase
  • FUC-TIV
  • FucT-IV
  • CD15
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P22083 # May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.

SIZE: 405 amino acids; 45570 Da

SUBCELLULAR LOCATION: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.

SIMILARITY: SwissProt: P22083 ## Belongs to the glycosyltransferase 10 family.
Molecular Weight 220 kDa Calculated
Product Usage Statements
Quality AssuranceEvaluated by Flow Cytometry with mouse embryonic stem cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8oC in undiluted aliquots for up to 6 months from date of receipt. Protect from light.
Packaging Information
Material Size100 tests
Global Trade Item Number
Catalogue Number GTIN
FCMAB117P 08436037126086