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06-1041 Anti-RIG-I, CT Antibody

06-1041
100 µg  
Purchase on Sigma-Aldrich

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Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue Number06-1041
DescriptionAnti-RIG-I, CT Antibody
Alternate Names
  • Probable ATP-dependent RNA helicase DDX58
  • DEAD box protein 58
  • Retinoic acid-inducible gene 1 protein
  • RIG-1
  • Retinoic acid-inducible gene I protein
  • RIG-I
Background InformationRetinoic acid-inducible gene 1 (RIG-1, DDX58) is a cytoplasmic protein belonging to the family of RIG-1-like receptor (RLR) family. It is a multidomain protein containing an N-terminal caspase recruitment domain (CARD); a DExD/H box helicase domain; and a C-terminal repression domain. RIG-1 has a well-documented role in innate immunity, as a virus-sensing protein that detects viral RNA molecules and induces the production of IFN-β through activation of the inflammasome complex.
References
Product Information
FormatAffinity Purified
Control
  • Untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours.
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationAnti-RIG-I, C-terminus Antibody is an antibody against RIG-I, C-terminus for use in Western Blotting.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to the C-terminus of human RIG-I.
EpitopeC-terminus
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
SpecificityThis antibody recognizes the C-terminus of RIG-I.
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • DDX58
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~102 kDa observed
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for 12 hours.

Western Blot Analysis: 1 µg/mL of this antibody detected RIG-I in 10 µg of untreated A549 cell lysate and A549 cell lysate infected with 40 HAU/mL of SeV for12 hours..
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
06-1041 04053252440236

Documentation

Anti-RIG-I, CT Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-RIG-I, CT Antibody Certificates of Analysis

TitleLot Number
Anti-RIG-I, C-terminus - 3238050 3238050
Anti-RIG-I, C-terminus - 3384864 3384864
Anti-RIG-I, C-terminus - Q2009198 Q2009198
Anti-RIG-I, C-terminus -2578590 2578590
Anti-RIG-I, C-terminus -2591894 2591894
Anti-RIG-I, C-terminus -2603856 2603856
Anti-RIG-I, C-terminus -2624230 2624230
Anti-RIG-I, C-terminus -2660182 2660182
Anti-RIG-I, C-terminus -2700255 2700255
Anti-RIG-I, C-terminus -2756674 2756674