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MAB3418B Anti-MAP2 Antibody, clone AP20, Biotin Conjugated

Anti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: Map2, Mtap2 UniProt Number: Q0IIA8
MAB3418B
100 µL  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, M, R, B, ChICCMBiotinMonoclonal Antibody
Description
Catalogue NumberMAB3418B
DescriptionAnti-MAP2 Antibody, clone AP20, Biotin Conjugated
Alternate Names
  • Microtubule-associated protein 2
  • MAP-2
  • MAP2
Background InformationThe microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.
References
Product Information
FormatBiotin
Control
  • Rat cortex tissue
PresentationPurified mouse monoclonal IgG conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Quality LevelMQ100
Applications
ApplicationAnti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.
Key Applications
  • Immunocytochemistry
Application NotesImmunocytochemistry Analysis: A 1:25 dilution from a representative lot detected MAP2 in rat E18 primary cortex cells.
Biological Information
ImmunogenBovine brain microtubule protein
CloneAP20
HostMouse
IsotypeIgG
Species Reactivity
  • Human
  • Mouse
  • Rat
  • Bovine
  • Chicken
Species Reactivity NoteDemonstrated to react with Rat. Predicted to react with Chicken, Human, and Mouse based on 100% sequence homology. Predicted to react with Bovine based on immunogen design.
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Map2
  • Mtap2
Purification MethodProtein G Purified
UniProt Number
Molecular WeightThe unconjugated parent antibody (Cat. No. MAB3418) has an observed molecular weight at ~230 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunohistochemistry in rat cortex tissue.

Immunohistochemistry Analysis: A 1:25 dilution of this antibody detected MAP2 in rat cortex tissue.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8 °C in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MAB3418B 04053252647734

Documentation

Anti-MAP2 Antibody, clone AP20, Biotin Conjugated SDS

Title

Safety Data Sheet (SDS) 

Anti-MAP2 Antibody, clone AP20, Biotin Conjugated Certificates of Analysis

TitleLot Number
Anti-MAP2, clone AP20, Biotin -2735800 2735800
Anti-MAP2, clone AP20, Biotin Conjugated 2978910
Anti-MAP2, clone AP20, Biotin Conjugated - 2391151 2391151
Anti-MAP2, clone AP20, Biotin Conjugated - 2814734 2814734
Anti-MAP2, clone AP20, Biotin Conjugated - 3180908 3180908
Anti-MAP2, clone AP20, Biotin Conjugated - 3470745 3470745
Anti-MAP2, clone AP20, Biotin Conjugated - 3878842 3878842
Anti-MAP2, clone AP20, Biotin Conjugated - 4030991 4030991
Anti-MAP2, clone AP20, Biotin Conjugated - 4215004 4215004
Anti-MAP2, clone AP20, Biotin Conjugated - 4252108 4252108
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