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ABE335 Anti-FOXL2 Antibody

This Anti-FOXL2 Antibody is validated for use in Western Blotting for the detection of FOXL2.

Anti-FOXL2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Epigenetics & Nuclear Function Research Sub-Category: Chromatin Biology Gene Symbol: FOXL2 UniProt Number: P58012
ABE335
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBRbAffinity PurifiedPolyclonal Antibody
Description
Catalogue NumberABE335
DescriptionAnti-FOXL2 Antibody
Alternate Names
  • Forkhead box protein L2
Background InformationForkhead box protein L2 (FOXL2) is a fork-head transcription factor that is expressed in developing gonad and in granulosa cells of the mature ovary. It plays a role in repressing the development of testis, and facilitating the differentiation and maintenance of the ovary. Mutations in the FOXL2 gene result in blepharophimosis ptosis epicanthus inversus (BPES) syndrome, which is characterized by craniofacial defects and premature ovarian failure. FOXL2 has also been implicated in the development of ovarian granulosa cell tumors.
References
Product Information
FormatAffinity Purified
Control
  • Human pituitary
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis Anti-FOXL2 Antibody is validated for use in Western Blotting for the detection of FOXL2.
Key Applications
  • Western Blotting
Biological Information
ImmunogenKLH-conjugated linear peptide corresponding to human FOXL2.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Species Reactivity NoteDemonstrated to react with Human. Predicted to react with Mouse, Bovine, Porcine, and Rabbit based on 100% sequence homology. Other homologies: Chicken (77% sequence homology).
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • FOXL2
Purification MethodAffinity Purfied
UniProt Number
Molecular Weight~50 kDa observed. An uncharacterized band may appear at ~25 kDa in some lysates. The calculated molecular weight is 39 kDa, however FOXL2 has been shown as a ~50 kDa band in western blots (Marongiu, M., et al. (2010). PLOS One. 5(3):1-9).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blot in human pituitary tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FOXL2 in 10 µg of human pituitary tissue lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABE335 04053252551796