Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

MABN709 Anti-DKK1, clone 2H2 Antibody

MABN709
100 µL  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HWBMAscitesMonoclonal Antibody
Description
Catalogue NumberMABN709
DescriptionAnti-DKK1, clone 2H2 Antibody
Alternate Names
  • Dickkopf-related protein 1
  • Dickkopf-1
  • Dkk-1
  • hDkk-1
  • SK
  • DKK1
Background Informationdickkopf homolog 1 (Xenopus laevis), also known as SK is a member of the dickkopf family. DKK1 is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.
References
Product Information
FormatAscites
PresentationMouse monoclonal IgG2b ascitic fluid containing 0.03% sodium azide.
Quality LevelMQ300
Applications
Key Applications
  • Western Blotting
Biological Information
ImmunogenPurified recombinant fragment of DKK1 expressed in E. Coli.
Clone2H2
ConcentrationPlease refer to lot specific datasheet.
HostMouse
IsotypeIgG2b
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Gene Symbol
  • DKK1
  • UNQ492/PRO1008
Purification MethodUnpurified
UniProt Number
Molecular Weight~68 kDa observed. Uncharacterized bands may be observed in some lysate(s).
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Western Blotting in Hek293 and DKK1-hIgGFc transfected HEK293 cell lysates.

Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected DKK1 in hIgGFc transfected HEK293 cell lysate.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Packaging Information
Material Size100 µL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
MABN709 04055977172010