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MABF455 Anti-CD80 (B7-1) Antibody (mouse), PE, clone 16-10A1

This armenian hamster monoclonal antibody Anti-CD80 (B7-1) (mouse), PE, clone 16-10A1 validated for use in IP, IHC, Immunofluorescence & Flow Cytometry for the detection of CD80 (B7-1).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Gene Symbol: Cd80 UniProt Number: Q00609
MABF455
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
MIP, IHC, IF, FCAHmPEMonoclonal Antibody
Description
Catalogue NumberMABF455
DescriptionAnti-CD80 (B7-1) Antibody (mouse), PE, clone 16-10A1
Alternate Names
  • T-lymphocyte activation antigen CD80
  • Activation B7-1 antigen
  • B7
  • CD80
Background InformationThe 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
Product Information
FormatPE
PresentationPurified Armenian Hamster Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Quality LevelMQ100
Applications
ApplicationThis armenian hamster monoclonal antibody Anti-CD80 (B7-1) (mouse), PE, clone 16-10A1 validated for use in IP, IHC, Immunofluorescence & Flow Cytometry for the detection of CD80 (B7-1).
Key Applications
  • Immunoprecipitation
  • Immunohistochemistry
  • Immunofluorescence
  • Flow Cytometry
Biological Information
ImmunogenImmunogen information for this antibody is proprietary information.
Clone16-10A1
Concentration0.2 mg/mL
HostArmenian Hamster
IsotypeIgG
Species Reactivity
  • Mouse
Antibody TypeMonoclonal Antibody
Gene Symbol
  • Cd80
Purification MethodSize Exclusion Chromatography
UniProt Number
Product Usage Statements
Quality AssuranceThe monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 µg of this antibody detected CD80in one million C57Bl/6 splenocytes.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsIt is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
Packaging Information
Material Size100 µg
Global Trade Item Number
Catalogue Number GTIN
MABF455 04053252960444