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575003 α-Synuclein A53T, Human, Recombinant, E. coli

575003
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
575003-200UG Plastic ampoule 200 μg
575003-UG Glass bottle
Description
OverviewRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. A point mutant (A53T) of α-synuclein gene that has been linked to autosomal dominant early-onset Parkinson’s disease (PD).
Catalogue Number575003
Brand Family Calbiochem®
References
ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
Park, S.M., et al. 2002. Blood 100, 2506.
Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
Product Information
FormLiquid
FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage -20°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
575003-200UG 04055977189209
575003-UG 04061839404854

Documentation

α-Synuclein A53T, Human, Recombinant, E. coli SDS

Title

Safety Data Sheet (SDS) 

α-Synuclein A53T, Human, Recombinant, E. coli Certificates of Analysis

TitleLot Number
575003

References

Reference overview
Lashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
Park, S.M., et al. 2002. Blood 100, 2506.
Polymeropoulos, M.H., et al. 1997. Science 276, 2045.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-September-2008 RFH
DescriptionRecombinant, human α-synuclein containing an A53T mutation and expressed in E. coli. α-synuclein is an acidic neuronal protein of 140 amino acids that has been implicated in the pathogenesis of Parkinson's disease and related neurodegenerative disorders. α-Synuclein (A53T) is a point mutant of the α-synuclein gene that has been linked to autosomal dominant early onset Parkinson's Disease (PD). The apparent molecular weight on SDS-PAGE is ~19-20 kDa.
FormLiquid
FormulationIn 100 mM NaCl, 20 mM Tris-HCl, pH 7.5.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE
Storage Avoid freeze/thaw
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
Toxicity Standard Handling
ReferencesLashuel, H.A., et al. 2002. J. Mol. Biol. 322, 1089.
Park, S.M., et al. 2002. Blood 100, 2506.
Polymeropoulos, M.H., et al. 1997. Science 276, 2045.