565764 Sigma-Aldrichγ-Secretase Substrate, Fluorogenic - Calbiochem
An internally quenched fluorogenic peptide substrate containing the C-terminal β-APP (amyloid β-peptide precursor protein) amino acid sequence that is cleaved by γ-secretase.
More>> An internally quenched fluorogenic peptide substrate containing the C-terminal β-APP (amyloid β-peptide precursor protein) amino acid sequence that is cleaved by γ-secretase. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: NMA-GGVVIATVK(DNP)-DRDRDR-NH₂
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Overview
Products
| Catalogue Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 565764-1MG | Plastic ampoule | 1 mg |
| References | |
|---|---|
| References | Farmery, M.R., et al. 2003. J. Biol. Chem. 278, 24277. |
| Product Information | |
|---|---|
| ATP Competitive | N |
| Form | Yellow Lyophilized |
| Formulation | Supplied as a trifluoroacetate salt. |
| Hill Formula | C₇₀H₁₁₆N₂₆O₁₈ |
| Chemical formula | C₇₀H₁₁₆N₂₆O₁₈ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Quality Level | MQ100 |
| Biological Information | |
|---|---|
| Primary Target | γ-secretase |
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Peptide Sequence | NMA-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Lys(DNP)-D-Arg-D-Arg-D-Arg-NH₂ |
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Global Trade Item Number | |
|---|---|
| Catalogue Number | GTIN |
| 565764-1MG | 04055977267730 |